Drugs that target and destroy phosphorylated-p68 (P-p68), an RNA helicase, have the potential to kill cancer, without damaging other tissues as chemotherapy does. P-p68 has recently garnered attention as a molecular target in cancer therapy. It is an ideal target because P-p68 is overexpressed in cancer cells but absent in normal cells. P-p68 has shown to increase the activity of cancer related genes including cyclin D1, c-jun and c-myc. It has a key role in tumor progression and cancer metastasis….
- The Bio Connection -