- A Novel Anti-Cancer Agent, 1-(3,5-Dimethoxyphenyl)-4-[(6-Fluoro-2-Methoxyquinoxalin-3-yl)Aminocarbonyl] Piperazine (RX-5902), Interferes With b-Catenin Function Through Y593 Phospho-p68 RNA Helicase.
(Journal of Cellular Biochemistry, 2015, 116, 1595–1601)[Link] - A Novel Cytidine Analog, RX-3117, Shows Potent Efficacy in Xenograft Models, even in Tumors that Are Resistant to Gemcitabine.
(Anticancer Research. 2014, 34, 6951 – 6960)[Link] - Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360).
(Invest New Drugs. 2013 Sep 19.)[Link] - Fluorocyclopentenyl-cytosine with Broad Spectrum and Potent Antitumor Activity.
(J Med Chem. 2012 May 10;55(9):4521-5. Epub 2012 May 1)[Link] - Synthesis, anticancer activity and pharmacokinetic analysis of 1-[(substituted
2-alkoxyquinoxalin-3-yl)aminocarbonyl]-4-(hetero)arylpiperazine derivatives.
(Bioorganic & Medicinal Chemistry 20 (2012) 1303–1309)[Link] - Synthesis and anticancer activity of new 1-[(5 or 6-substituted 2-alkoxyquinoxalin-3-yl)aminocarbonyl]-4-hetero)arylpiperazine derivatives.
(Bioorganic & Medicinal Chemistry, November 2010, 18(22,15), 7966-7974)[Link] - Development of 3-aryl-1-isoquinolinamines as potent antitumor agents based on CoMFA.
(European Journal of Medicinal Chemistry, November 2010, 45(11), 5493-5497)[Link] - Synthesis, in vitro and in vivo evaluation of 3-arylisoquinolinamines as potent antitumor agents.
(Bioorganic & Medicinal Chemistry Letters, September 2010 20(17,1), 5277-5281)[Link] - Antitumor activity of a novel antisense oligonucleotide against Akt1.
(Journal of Cellular Biochemistry, November 2009, 108(4) 832–838) [Link] - QSID Tool: a new three-dimensional QSAR environmental tool.
(Journal of Computer-Aided Molecular Design, December 2008, 22(12), 873-883)[Link] - In Vivo and In Vitro Effects of a HIF-1a Inhibitor,RX-0047.
(Journal of Cellular Biochemistry, June 2008, 104(3), 985–994)[Link] - SYNTHESIS AND ANTITUMOR ACTIVITY OF FLUOROCYCLOPENTENYL-PYRIMIDINES.
(Nucleosides Nucleotides Nucleic Acids, 2007, 26(6-7), 713-6)[Link] - Requirement of hCenexin for Proper Mitotic Functions of Polo-Like Kinase 1 at the Centrosomes.
(Molecular and Cellular Biology, November 2006, 26(22), 8316-8335)[Link] - Design, synthesis, and anticancer activity of fluorocyclopentenyl-pyrimidines.
(Nucleic Acids Symp Ser, September 2005, 49(1), 107-108)[Link]